Fermentation and Purification

• Project management
• High throughput screening
• Secure management of cell banks
• RDNA strains and processes
• Process design and optimisation
• Advanced instrumentation
• Automation of process steps, including on-line models, parameter estimation and product handling (S 88)
• Automation of product handling and ‘lights out’ operation (S 88)
• Simulation, expert systems, neural nets, genetic algorithms,
• Equipment design using latest technology
• All types of reactor configuration from bubble column, to stirred tank, to solid state types
• Hygienic and aseptic design
• Validation
• All cell types
• Regulatory and legal requirements
• Risk management
• In-situ extraction
• Membrane processes
• Sterile filtration
• Chromatographic processes
• Solvent extraction
• Aseptic packaging to 1000L
• Handling of highly volatile/highly odorous materials